1-[(2-fluorophenyl)methyl]hydrazine
(2-fluorobenzyl)hydrazine
CAS: 51859-98-4
Molecular Formula: C7H9FN2
1-[(2-fluorophenyl)methyl]hydrazine - Names and Identifiers
1-[(2-fluorophenyl)methyl]hydrazine - Physico-chemical Properties
| Molecular Formula | C7H9FN2 |
| Molar Mass | 140.16 |
| Density | 1.144±0.06 g/cm3(Predicted) |
| Boling Point | 265.8±23.0 °C(Predicted) |
| Flash Point | 114.6°C |
| Vapor Presure | 0.00895mmHg at 25°C |
| pKa | 6.74±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.537 |
1-[(2-fluorophenyl)methyl]hydrazine - Introduction
(2-fluorobenzyl)hydrazine is an organic compound with the chemical formula C7H9FN2. The following is a description of the nature, use, preparation and safety information of (2-fluorobenzyl)hydrazine:
Nature:
-Appearance:(2-fluorobenzyl)hydrazine is a colorless to pale yellow liquid.
-Melting point and boiling point: Its melting point is -39°C and boiling point is 165-170°C.
-Solubility:(2-fluorobenzyl)hydrazine soluble in organic solvents such as ether and methylene chloride, slightly soluble in water.
Use:
-Chemical synthesis:(2-fluorobenzyl)hydrazine can be used as an intermediate in organic synthesis to prepare other compounds, such as drugs and dyes.
-Drug research:(2-fluorobenzyl)hydrazine can be used to synthesize biologically active chemical reagents and drugs.
Preparation Method:
(2-fluorobenzyl)hydrazine can be prepared by the following methods:
1. Hydrogenation of 2-fluorobenzylamine with a hydrogen catalyst (such as palladium/activated carbon) in a reaction solvent (such as methanol or isopropanol).
2. 2-Fluorobenzoyl fluoride is reacted with hydrazine under alkaline conditions.
Safety Information:
- (2-fluorobenzyl)hydrazine has certain toxicity and corrosiveness, please use carefully.
-Wear appropriate protective equipment such as gloves and goggles when used.
-Avoid contact with skin, eyes and clothing.
-Operate in a well-ventilated place and avoid inhaling its vapor or gas.
-Avoid contact with oxidants and strong acids.
-Waste disposal shall comply with local regulations.
Nature:
-Appearance:(2-fluorobenzyl)hydrazine is a colorless to pale yellow liquid.
-Melting point and boiling point: Its melting point is -39°C and boiling point is 165-170°C.
-Solubility:(2-fluorobenzyl)hydrazine soluble in organic solvents such as ether and methylene chloride, slightly soluble in water.
Use:
-Chemical synthesis:(2-fluorobenzyl)hydrazine can be used as an intermediate in organic synthesis to prepare other compounds, such as drugs and dyes.
-Drug research:(2-fluorobenzyl)hydrazine can be used to synthesize biologically active chemical reagents and drugs.
Preparation Method:
(2-fluorobenzyl)hydrazine can be prepared by the following methods:
1. Hydrogenation of 2-fluorobenzylamine with a hydrogen catalyst (such as palladium/activated carbon) in a reaction solvent (such as methanol or isopropanol).
2. 2-Fluorobenzoyl fluoride is reacted with hydrazine under alkaline conditions.
Safety Information:
- (2-fluorobenzyl)hydrazine has certain toxicity and corrosiveness, please use carefully.
-Wear appropriate protective equipment such as gloves and goggles when used.
-Avoid contact with skin, eyes and clothing.
-Operate in a well-ventilated place and avoid inhaling its vapor or gas.
-Avoid contact with oxidants and strong acids.
-Waste disposal shall comply with local regulations.
Last Update：2024-04-09 02:00:46
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